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Pain Information Active Ingredient Information Doxylamine Succinate
Doxylamine Succinate
Doxylamine succinate is an ethanolamine derivative antihistamine that has a tendency to induce sedation. This is why it is used to help adults who experience occasional sleeplessness or insomnia. Its calmative properties help in the treatment of migraines and tension headaches, reducing the anxiety that can perpetuate pain.
Doxylamine succinate is an antihistamine that blocks the effectiveness of the substance histamine. It also has anticholinergic and antiemetic properties. Doxylamine succinate is used in some products to provide relief from tension headaches and migraines, as well as helping to relieve toothache, backache, and post-operative pain.
Doxylamine succinate taken orally is easily absorbed by the gastrointestinal tract. It has an eilmination half-life of about nine hours. Approximately 60% is excreted in the urine as unchanged doxylamine, as well as nordoxylamine and dinordoxylamine.